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Bioengineered solutions for better immunotherapies

Associated Publications

Alatoom A, et al. Advanced Biology. 2022. doi: 10.1002/adbi.202200173.
Alatoom A, et al. Advanced Biosystems. 2020. doi: 10.1002/adbi.202000039.

Cell-based immunotherapies, the use of one’s own immune cells to boost immunity against certain diseases has tremendous potential. For example, genetically modified T-cells have been successfully used against blood cancers, but the same approach falls short against solid cancers. Based on our believe that cell-based immunotherapies can be further optimized for efficiency and efficacy through addressing the mechanical and physicals cues that suppress immune potency. We are bioengineering solutions to better expand fitter T-cells to overwhelm cancer.

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